William James Mayo was an American physician and surgeon, best known for co-founding the Mayo Clinic in Rochester, Minnesota. Born on June 29, 1861, he played a significant role in advancing medical practices and patient care. His commitment to collaboration among healthcare professionals helped establish the clinic as a leading medical institution. Mayo's innovative approach to medicine emphasized the importance of teamwork and research. Alongside his brother, Charles Horace Mayo, he developed a model of healthcare that prioritized patient-centered care. Their efforts contributed to the growth of the Mayo Clinic into a renowned center for medical excellence and education.