WNT4 is a gene that plays a crucial role in the development of the reproductive system and kidneys. It is part of the Wnt signaling pathway, which is important for cell communication and growth. WNT4 is particularly significant in the formation of female reproductive organs during embryonic development. Mutations or alterations in the WNT4 gene can lead to various health issues, including Müllerian agenesis, a condition where the uterus and other female reproductive structures do not develop properly. Additionally, WNT4 is involved in kidney function, and its dysfunction can contribute to renal diseases.