Urea Cycle
The Urea Cycle is a series of biochemical reactions that occur in the liver, converting toxic ammonia into urea, which can be safely excreted in urine. This process is essential for removing excess nitrogen from the body, primarily generated from the breakdown of proteins. The cycle involves several key enzymes and intermediates, including ornithine, citrulline, and aspartate.
During the Urea Cycle, ammonia combines with carbon dioxide to form urea through a series of steps. This cycle not only helps maintain nitrogen balance but also plays a crucial role in metabolic processes. Disruptions in the Urea Cycle can lead to serious health issues, including hyperammonemia.