Uncoupling Protein 2 (UCP2) is a protein found in the inner mitochondrial membrane of cells. It plays a role in regulating energy metabolism by dissipating the proton gradient generated during cellular respiration. This process can lead to reduced ATP production and increased heat generation, which may help in managing energy balance and reducing oxidative stress. UCP2 is involved in various physiological processes, including metabolism, thermogenesis, and apoptosis. It is expressed in several tissues, including the brain, adipose tissue, and pancreas. Research suggests that UCP2 may have implications in conditions like obesity and diabetes by influencing energy expenditure and insulin sensitivity.