The term "Twenty-First" typically refers to the twenty-first position in a sequence, such as in counting or ranking. It can also denote the twenty-first year of a century, like the 21st century, which began in the year 2001 and will end in 2100. In various contexts, "Twenty-First" may relate to specific events, such as the Twenty-First Amendment to the United States Constitution, which repealed the prohibition of alcohol in 1933. Additionally, it can refer to cultural or historical milestones that occurred in the twenty-first year of a particular century or era.