Transforming Growth Factor
Transforming Growth Factor (TGF) is a group of proteins that play a crucial role in regulating cell growth, differentiation, and immune responses. It is involved in various biological processes, including wound healing and tissue repair. TGF is particularly important in controlling inflammation and maintaining the balance between cell proliferation and apoptosis (programmed cell death).
There are several types of TGF, with TGF-β being the most studied. This specific type is known for its ability to inhibit immune responses and promote fibrosis, which is the thickening and scarring of connective tissue. Dysregulation of TGF signaling can lead to various diseases, including cancer and autoimmune disorders.