Tissue death, also known as necrosis, occurs when cells in a specific area of the body die due to injury, lack of blood flow, or infection. This process can result from various factors, including trauma, inadequate oxygen supply, or exposure to harmful substances. When tissue dies, it can lead to inflammation and further complications in the surrounding areas. There are different types of necrosis, such as coagulative necrosis, which typically affects solid organs like the heart, and liquefactive necrosis, which often occurs in the brain. Understanding the causes and types of tissue death is essential for effective treatment and prevention of further damage.