The Sinclair Method is a treatment approach for alcohol use disorder that involves the use of the medication naltrexone. This method is based on the principle of pharmacological extinction, where the medication helps reduce cravings for alcohol when taken before drinking. Over time, this can lead to a decrease in alcohol consumption and a change in drinking behavior. The method was developed by Dr. John Sinclair, who discovered that naltrexone could help individuals recondition their relationship with alcohol. By combining medication with continued drinking, the Sinclair Method aims to help individuals regain control over their drinking habits without requiring complete abstinence initially.