The TNF receptor is a type of protein found on the surface of cells that plays a crucial role in the immune system. It binds to tumor necrosis factor (TNF), a signaling molecule involved in inflammation and immune responses. When TNF attaches to its receptor, it triggers various cellular processes, including cell survival, proliferation, and apoptosis (programmed cell death). There are several types of TNF receptors, including TNFR1 and TNFR2, each with distinct functions. These receptors are important in regulating inflammation and can be involved in various diseases, such as autoimmune disorders and cancer. Understanding TNF receptors helps researchers develop targeted therapies for these conditions.