TNFR2, or Tumor Necrosis Factor Receptor 2, is a protein found on the surface of certain cells in the body. It plays a crucial role in the immune system by helping to regulate inflammation and cell survival. TNFR2 interacts with specific molecules, including TNF-alpha, to trigger various cellular responses that can influence immune reactions. This receptor is important in both health and disease. In normal conditions, TNFR2 helps maintain a balanced immune response, but in some diseases, such as autoimmune disorders and cancers, its activity can become dysregulated. Understanding TNFR2 is essential for developing targeted therapies in these conditions.