T cell receptors
T cell receptors (TCRs) are specialized proteins found on the surface of T cells, a type of white blood cell crucial for the immune response. These receptors recognize specific fragments of proteins, known as antigens, that are presented by other cells. When a TCR binds to its corresponding antigen, it triggers the T cell to activate and respond to potential threats, such as infections or cancer.
Each T cell has a unique TCR, allowing the immune system to identify a wide variety of pathogens. The diversity of TCRs is generated through a process called V(D)J recombination, which rearranges gene segments to create different receptor combinations. This diversity is essential for the immune system's ability to adapt and respond effectively to numerous challenges.