Sarcoglycans are a group of proteins found in muscle cells, specifically in the cell membrane. They play a crucial role in connecting the muscle fibers to the surrounding extracellular matrix, helping to maintain muscle integrity and function. There are four main types of sarcoglycans: α, β, γ, and δ, each contributing to the stability of muscle tissue. Mutations in the genes encoding sarcoglycans can lead to various forms of muscular dystrophy, such as Limb-Girdle Muscular Dystrophy. This condition results in progressive muscle weakness and degeneration, highlighting the importance of sarcoglycans in muscle health and disease.