Limb-Girdle Muscular Dystrophy (LGMD) is a group of genetic disorders that cause progressive weakness and wasting of the muscles around the hips and shoulders. This condition affects the limb-girdle muscles, which are essential for movement and stability. Symptoms typically appear in childhood or early adulthood, but they can vary widely among individuals. There are several types of LGMD, each caused by different genetic mutations. Diagnosis often involves genetic testing, muscle biopsies, and clinical evaluations. While there is currently no cure, physical therapy and supportive care can help manage symptoms and improve quality of life for those affected.