SCNN1B is a gene that encodes a protein known as the beta subunit of the epithelial sodium channel (ENaC). This protein plays a crucial role in regulating sodium balance and fluid homeostasis in the body, particularly in tissues like the kidneys and lungs. Proper functioning of SCNN1B is essential for maintaining blood pressure and electrolyte levels. Mutations in the SCNN1B gene can lead to various health issues, including Liddle syndrome, a genetic disorder characterized by hypertension and low levels of potassium in the blood. Understanding SCNN1B is important for researchers studying sodium transport and related diseases, as it can provide insights into potential treatments and therapies.