River Blindness, also known as onchocerciasis, is a disease caused by a parasitic worm called Onchocerca volvulus. This worm is transmitted to humans through the bites of infected blackflies, which are often found near rivers. The disease primarily affects people in rural areas of Sub-Saharan Africa, leading to severe itching, skin rashes, and, in some cases, vision loss. If left untreated, River Blindness can result in permanent blindness, making it a significant public health concern. Efforts to control the disease include distributing medications like ivermectin, which help kill the larvae of the parasite. Community awareness and prevention strategies are crucial in reducing the impact of this debilitating condition.