Rett Syndrome is a rare genetic disorder that primarily affects girls and is caused by mutations in the MECP2 gene. It typically appears between 6 months and 2 years of age, after a period of normal development. Symptoms include a loss of purposeful hand skills, difficulties with communication, and problems with movement and coordination. As the condition progresses, individuals may experience seizures, breathing irregularities, and cognitive impairments. While there is currently no cure for Rett Syndrome, early intervention and supportive therapies can help improve quality of life and manage symptoms.