Angelman Syndrome is a genetic disorder that primarily affects the nervous system. It is characterized by developmental delays, speech impairments, and difficulties with movement and balance. Individuals with this condition often exhibit a happy demeanor, frequent laughter, and a tendency to be easily excitable. The syndrome is caused by a loss of function of the UBE3A gene, which is located on chromosome 15. Diagnosis typically occurs in early childhood, and while there is no cure, therapies such as physical, occupational, and speech therapy can help improve quality of life and support development.