Re-Entry Syndrome refers to the psychological and emotional challenges faced by astronauts when they return to Earth after spending extended periods in space. This condition can manifest as anxiety, depression, or difficulty readjusting to everyday life. The experience of weightlessness and isolation in space can lead to a sense of disconnection upon returning home. The syndrome is particularly relevant for astronauts from programs like NASA or ESA, who may struggle with reintegrating into their families and communities. Support systems, including counseling and peer support, are essential for helping individuals navigate this transition and regain a sense of normalcy.