An R-Tree is a data structure used for indexing multi-dimensional information, such as geographical coordinates or spatial data. It organizes data in a hierarchical manner, allowing for efficient querying of spatial objects. Each node in an R-Tree contains a number of entries, which can represent either data objects or child nodes, and these entries are enclosed within minimum bounding rectangles. R-Trees are particularly useful in applications like geographic information systems (GIS), computer graphics, and robotics, where quick access to spatial data is essential. They support various operations, including insertion, deletion, and searching, making them a versatile choice for managing complex datasets.