Princess Maria Ana of Portugal was born on September 21, 1634, in Lisbon, Portugal. She was the daughter of King John IV of Portugal and Queen Luisa de Guzmán. Maria Ana became known for her beauty and grace, and she played a significant role in the royal court during her lifetime. In 1650, she married King Philip IV of Spain, which strengthened the ties between Portugal and Spain. Maria Ana served as the Queen consort of Spain until her death on May 16, 1692. Her marriage was part of a broader strategy to secure political alliances in the Iberian Peninsula.