Princess Antoinette of Brunswick-Wolfenbüttel was born on December 18, 1753, in Brunswick, Germany. She was a member of the House of Brunswick and the daughter of Duke Charles I of Brunswick-Wolfenbüttel and Princess Augusta of Great Britain. Antoinette's lineage connected her to various European royal families.
In 1770, she married Prince Ferdinand of Brunswick-Wolfenbüttel, strengthening political ties. The couple had several children, contributing to the continuation of their noble line. Antoinette's life was marked by her role in the court and her influence within the Brunswick region until her death on June 2, 1800.