Platelet-Derived Growth Factor Receptor
The Platelet-Derived Growth Factor Receptor (PDGFR) is a type of protein found on the surface of cells that plays a crucial role in cell growth, development, and healing. It binds to specific proteins called platelet-derived growth factors (PDGFs), which are involved in various biological processes, including wound healing and the formation of blood vessels.
PDGFR exists in two main forms, PDGFR-α and PDGFR-β, each with distinct functions and tissue distributions. Abnormal activation of PDGFR has been linked to several diseases, including certain types of cancer and fibrotic disorders, making it a target for therapeutic interventions in medical research.