Platelet-Derived Growth Factor (PDGF) is a protein that plays a crucial role in cell growth, division, and healing. It is primarily produced by platelets, which are small cell fragments in the blood that help with clotting. PDGF stimulates the proliferation of various cell types, including fibroblasts and smooth muscle cells, making it essential for tissue repair and regeneration. PDGF functions by binding to specific receptors on the surface of target cells, triggering a series of cellular responses. This process is vital in wound healing and the development of blood vessels, known as angiogenesis. Abnormal PDGF activity is associated with several diseases, including cancer and fibrosis.