The Plasmodium parasite is a single-celled organism responsible for causing malaria, a serious disease transmitted through the bites of infected Anopheles mosquitoes. There are several species of Plasmodium, with Plasmodium falciparum being the most deadly. Once inside the human body, the parasite multiplies in the liver and then infects red blood cells, leading to symptoms such as fever, chills, and fatigue. Malaria is prevalent in tropical and subtropical regions, affecting millions of people worldwide. Prevention methods include using insecticide-treated bed nets, indoor spraying, and taking antimalarial medications. Effective treatment typically involves a combination of drugs to target the Plasmodium species involved.