Flippases are specialized enzymes that facilitate the movement of phospholipids between the inner and outer layers of cell membranes. This process is crucial for maintaining the asymmetry of the lipid bilayer, which is essential for various cellular functions, including signaling and membrane fusion. These enzymes play a vital role in cellular processes such as apoptosis and vesicle trafficking. By ensuring that specific lipids are located in the correct membrane layer, flippases help regulate the overall structure and function of cells, contributing to the health and stability of cellular environments.