PPAR Family
The PPAR family, or Peroxisome Proliferator-Activated Receptors, consists of three main types: PPAR-alpha, PPAR-beta/delta, and PPAR-gamma. These nuclear receptors play crucial roles in regulating gene expression related to metabolism, inflammation, and cell differentiation. They are activated by various ligands, including fatty acids and their derivatives.
PPARs are important for maintaining energy balance and lipid metabolism in the body. PPAR-alpha primarily influences fatty acid oxidation in the liver, while PPAR-gamma is involved in glucose metabolism and fat cell differentiation. PPAR-beta/delta contributes to energy expenditure and has roles in muscle and fat tissue.