PPAR-gamma is a type of protein that belongs to the peroxisome proliferator-activated receptor (PPAR) family. It plays a crucial role in regulating fat cell development, glucose metabolism, and insulin sensitivity. By activating specific genes, PPAR-gamma helps control how the body uses and stores fats, making it important for maintaining energy balance. This protein is also a target for certain medications used to treat type 2 diabetes, as it can improve insulin sensitivity and lower blood sugar levels. Additionally, PPAR-gamma is involved in inflammation regulation, linking it to various metabolic and cardiovascular diseases.