Platelet-Derived Growth Factor (PDGF) is a protein that plays a crucial role in cell growth, development, and healing. It is primarily produced by platelets, which are small cell fragments in the blood that help with clotting. PDGF stimulates the proliferation and migration of various cell types, particularly fibroblasts, which are essential for tissue repair and regeneration. PDGF functions by binding to specific receptors on the surface of target cells, triggering a series of cellular responses. This process is vital in wound healing and tissue repair, as it helps to form new blood vessels and promotes the formation of connective tissue. Abnormal PDGF activity is associated with various diseases, including certain types of cancer.