Nicotiana rustica, commonly known as Aztec tobacco or wild tobacco, is a species of flowering plant in the nightshade family, Solanaceae. It is native to the Americas and is known for its high nicotine content, which is significantly greater than that of Nicotiana tabacum, the primary source of commercial tobacco. This plant typically grows to about 1 to 2 meters tall and produces large, green leaves and small, tubular flowers.
Traditionally, Nicotiana rustica has been used by indigenous peoples for ceremonial and medicinal purposes. It is often cultivated in gardens and is sometimes used in the production of traditional tobacco products. Due to its potent effects, it is less commonly used in modern commercial tobacco products compared to its relative, Nicotiana tabacum.