New York State Route 5S is a state highway located in New York, primarily serving the area between Schoharie and Amsterdam. It runs for approximately 30 miles, connecting various towns and providing access to local attractions and communities. The route begins at its junction with New York State Route 5 in Schoharie and travels northeast, eventually intersecting with New York State Route 67 in Amsterdam. Route 5S is known for its scenic views and is an important roadway for both residents and travelers in the region.