Neurokinin-2 (NK2) is a neuropeptide that plays a significant role in the body's nervous system. It is part of the tachykinin family, which includes other neuropeptides like substance P and neurokinin-1. NK2 primarily binds to the neurokinin-2 receptor, influencing various physiological processes, including pain perception, inflammation, and smooth muscle contraction. Research indicates that NK2 is involved in regulating functions in the respiratory and gastrointestinal systems. It may also play a role in mood regulation and stress responses. Understanding NK2's mechanisms can help in developing treatments for conditions like asthma and gastrointestinal disorders.