Mucocutaneous Leishmaniasis is a severe form of leishmaniasis caused by the parasite Leishmania and primarily affects the mucous membranes of the nose, mouth, and throat. It often develops after an initial skin infection, leading to painful lesions and potential disfigurement. This condition is most commonly found in regions of South America. Transmission occurs through the bite of infected sandflies, which are prevalent in tropical and subtropical areas. Diagnosis typically involves clinical examination and laboratory tests. Treatment may include medications such as antimonials or miltefosine, but early intervention is crucial to prevent complications.