Mevalonate Pathway
The Mevalonate Pathway is a crucial metabolic route in cells that produces important biomolecules, including cholesterol and certain isoprenoids. It begins with the conversion of acetyl-CoA into mevalonate, which is then transformed into various intermediates leading to the synthesis of these essential compounds. This pathway is vital for cellular functions and membrane integrity.
In humans and many other organisms, the Mevalonate Pathway is particularly significant for synthesizing cholesterol, which is necessary for cell membrane structure and hormone production. Additionally, it plays a role in generating isoprenoids, which are involved in various biological processes, including signaling and protein modification.