Mayer-Rokitansky-Küster-Hauser Syndrome (MRKH) is a congenital condition affecting females, characterized by the absence or underdevelopment of the uterus and vagina. It occurs during fetal development and can lead to challenges in menstruation and fertility, although external genitalia typically appear normal. Individuals with MRKH often have normal ovarian function, meaning they can produce eggs, but may require assisted reproductive technologies to conceive. The syndrome can also be associated with other anomalies, such as issues with the kidneys or spine, making early diagnosis and comprehensive care important for affected individuals.