Androgen Insensitivity Syndrome (AIS) is a genetic condition that affects sexual development in individuals with XY chromosomes. People with AIS are genetically male but may develop female physical traits because their bodies cannot respond to androgens, the hormones responsible for male characteristics. This can result in a range of physical presentations, from typical female anatomy to ambiguous genitalia. AIS can be classified into complete and partial forms. In complete AIS, individuals have a female appearance and are often raised as girls, while in partial AIS, some male characteristics may be present. Diagnosis typically occurs during puberty or through genetic testing, and management may involve hormone therapy and psychological support.