Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is a congenital condition affecting females, characterized by the absence or underdevelopment of the uterus and vagina. It occurs during fetal development and is often diagnosed during adolescence when menstruation does not begin. Individuals with MRKH typically have normal ovarian function and secondary sexual characteristics, such as breast development. The condition can impact reproductive health, but many women with MRKH can still achieve pregnancy through assisted reproductive technologies, such as surrogacy or adoption.