Mast Cell Activation Syndrome (MCAS) is a condition where the body's mast cells, which are a type of immune cell, become overly active. These cells release various chemicals, including histamine, leading to symptoms such as itching, hives, abdominal pain, and difficulty breathing. MCAS can be triggered by various factors, including certain foods, medications, and environmental elements. Diagnosis of MCAS can be challenging, as symptoms often mimic other conditions. Treatment typically involves avoiding known triggers and may include medications like antihistamines to manage symptoms. Understanding and managing MCAS is essential for improving the quality of life for those affected.