MSH2 is a gene that plays a crucial role in the body's ability to repair DNA. It is part of a group of proteins known as mismatch repair proteins, which help correct errors that occur during DNA replication. Proper functioning of MSH2 is essential for maintaining genetic stability and preventing mutations. Mutations in the MSH2 gene can lead to various health issues, including an increased risk of certain cancers, such as Lynch syndrome. This condition is characterized by a higher likelihood of developing colorectal and other types of cancer due to the impaired DNA repair process associated with faulty MSH2 function.