Lamellar Ichthyosis is a rare genetic skin disorder characterized by the presence of thick, scaly patches on the skin. This condition is caused by mutations in the TGM1 gene, which plays a crucial role in skin barrier formation. Individuals with lamellar ichthyosis often experience dry, cracked skin that can lead to discomfort and increased risk of infections. The scales typically appear at birth or shortly after and can cover large areas of the body. Treatment focuses on managing symptoms, primarily through the use of moisturizers and topical therapies to improve skin hydration and reduce scaling. Regular dermatological care is essential for maintaining skin health.