Kuru disease is a rare and fatal neurodegenerative disorder that was primarily found among the Fore people of Papua New Guinea. It is caused by prions, which are misfolded proteins that lead to brain damage. Symptoms include tremors, loss of coordination, and severe psychological changes. The disease was linked to the practice of endocannibalism, where the Fore people consumed the bodies of deceased relatives as a sign of respect. This practice allowed the prions to spread within the community. Kuru has largely disappeared since the cessation of these rituals and increased awareness of the disease.