The Japanese Encephalitis virus (JEV) is a mosquito-borne virus that can cause inflammation of the brain, known as encephalitis. It is primarily found in rural areas of Asia and the Western Pacific, where the Culex mosquito species thrive. Most infections are mild or asymptomatic, but severe cases can lead to neurological complications and even death. Vaccination is the most effective way to prevent JEV infection, especially for people living in or traveling to high-risk areas. The virus is transmitted through the bite of infected mosquitoes, and there is no specific antiviral treatment for the disease, making prevention crucial.