Isabella d'Este (1474-1539) was an influential Italian noblewoman and a prominent figure of the Renaissance. Born into the Este family, she became the Marchioness of Mantua through her marriage to Francesco Gonzaga. Isabella was known for her intelligence, political acumen, and patronage of the arts, which helped shape the cultural landscape of her time. As a patron, Isabella supported artists like Leonardo da Vinci and Raphael, commissioning works that reflected her taste and status. She also maintained a renowned court that attracted scholars and artists, making her a key player in the cultural exchanges of the Italian city-states.