Inflammasomes
Inflammasomes are multi-protein complexes found in immune cells that play a crucial role in the body's defense against infections and injuries. They detect harmful stimuli, such as pathogens or cellular damage, and activate inflammatory responses. This process helps the body fight off infections and promotes healing.
When activated, inflammasomes trigger the production of pro-inflammatory cytokines, such as interleukin-1β and interleukin-18. These cytokines signal other immune cells to respond, leading to inflammation. While this response is essential for protection, excessive inflammasome activation can contribute to various inflammatory diseases, highlighting the need for balanced immune regulation.