The Indian Hedgehog (Ihh) is a signaling protein that plays a crucial role in the Hedgehog signaling pathway, which is important for cell growth and development. It is involved in various biological processes, including embryonic development and tissue regeneration. Ihh is primarily expressed in the skeleton and cartilage, influencing the formation of bones and the growth of limbs. Ihh is one of three hedgehog proteins, alongside Sonic Hedgehog (Shh) and Desert Hedgehog (Dhh). These proteins are essential for proper cellular communication during development. Abnormalities in the Ihh signaling pathway can lead to various diseases, including certain types of cancer and developmental disorders.