Incilius alvarius, commonly known as the Sonoran Desert toad, is a large toad species native to the southwestern United States and northern Mexico. It typically inhabits arid regions, often found near seasonal water sources. This toad is known for its distinctive appearance, featuring a robust body and smooth, warty skin that can vary in color from brown to green. The Sonoran Desert toad is notable for its secretions, which contain a potent substance called 5-MeO-DMT. This compound has gained attention for its psychoactive properties, leading to interest in its use in traditional and modern spiritual practices. However, the toad itself is not endangered and plays a vital role in its ecosystem.