IgA Nephropathy is a kidney disease characterized by the buildup of a protein called Immunoglobulin A (IgA) in the glomeruli, which are tiny filtering units in the kidneys. This accumulation can lead to inflammation and damage, affecting the kidneys' ability to filter waste from the blood effectively. Symptoms of IgA Nephropathy may include blood in the urine, swelling in the legs and feet, and high blood pressure. The exact cause is not fully understood, but it is believed to involve a combination of genetic and environmental factors. Treatment focuses on managing symptoms and slowing disease progression.