Iduronate Sulfatase is an enzyme that plays a crucial role in the breakdown of specific complex carbohydrates known as glycosaminoglycans. It helps to remove sulfate groups from iduronate, a sugar component found in these molecules. This process is essential for maintaining normal cellular function and tissue health. Deficiency of Iduronate Sulfatase leads to a genetic disorder called Mucopolysaccharidosis type II (Hunter syndrome). This condition results in the accumulation of glycosaminoglycans in the body, causing various health issues, including developmental delays and organ dysfunction. Early diagnosis and treatment can help manage symptoms and improve quality of life.