Hyper-IgM Syndrome is a rare immunodeficiency disorder characterized by an inability to produce adequate levels of immunoglobulin G (IgG) and immunoglobulin A (IgA). Individuals with this condition typically have high levels of immunoglobulin M (IgM) but low levels of other immunoglobulins, leading to increased susceptibility to infections. The syndrome is often caused by genetic mutations affecting B cells, which are crucial for producing antibodies. Symptoms may include recurrent infections, particularly in the respiratory and gastrointestinal tracts. Early diagnosis and treatment are essential to manage the condition and improve the quality of life for affected individuals.