Hutchinson-Gilford Progeria Syndrome (HGPS) is a rare genetic disorder that causes rapid aging in children. It is caused by a mutation in the LMNA gene, which leads to the production of an abnormal protein called progerin. This protein affects the stability of the cell nucleus, resulting in various health issues, including growth delays, hair loss, and cardiovascular problems. Children with HGPS typically appear normal at birth but begin to show symptoms within the first two years of life. The average lifespan for individuals with this condition is around 13 years, although some may live into their 20s. Research continues to explore potential treatments and therapies to improve the quality of life for those affected.