LMNA is a gene that provides instructions for making a protein called lamin A/C. This protein is essential for maintaining the structure and stability of the cell nucleus, which is the control center of the cell. Lamin A/C plays a crucial role in organizing the DNA and regulating gene expression. Mutations in the LMNA gene can lead to various genetic disorders, collectively known as laminopathies. These conditions can affect multiple systems in the body, leading to symptoms such as muscle weakness, heart problems, and premature aging. Examples of laminopathies include Hutchinson-Gilford progeria syndrome and muscular dystrophy.